Using two different controllers at once

I have an arcade with a Xin Mo USB controller and I have a couple generic SNES style paddles. Is it possible to have the SNES style controllers and Xin Mo controller work at the same time with RetroArch emulators? I’d like to be able to have the choice to either pick up the SNES paddle or use the arcade buttons depending on the game or emulator without having to unplug one or the other.